HCID 66745949, compound → HCID 66746220, compound

Participants

Reaction Steps

Prepared as in Example 1 from ethyl 4-amino-5-(2-cyclohexylethyl)-2-(2-ethoxy-2-oxoethyl)quinoline-3-carboxylate (Example 113a) as an orange solid (69%). 1H NMR (400 MHz, DMSO-d6) δ 0.89-0.92 (m, 2H), 1.14-1.29 (m, J4H), 1.44-1.49 (m, 2H), 1.56-1.66 (m, 4H), 1.73-1.76 (m, 1H), 3.15 (t, J=8.0 Hz, 2H), 3.70 (s, 2H), 7.09-7.11 (m, 1H), 7.38-7.42 (m, 1H), 7.46-7.51 (m, 2H). MS 338 (MH+-H2O).

Provenance & Evidence