Isopropylamine → HCID 66746794, compound

HRID 1467140Notes

Reaction equation

HRID 1467140 reaction equation
[OH:1][CH2:2][CH:3]1[CH2:8][CH2:7][CH:6]([C:9]([OH:11])=O)[CH2:5][CH2:4]1.[CH3:12][CH:13]([NH2:15])[CH3:14]>>[OH:1][CH2:2][CH:3]1[CH2:4][CH2:5][CH:6]([C:9]([NH:15][CH:13]([CH3:14])[CH3:12])=[O:11])[CH2:7][CH2:8]1

Participants

3

Reactant 2

HCID 6363IsopropylamineHCID 202819Cyclohexanecarboxylic acid, 4-(hydroxymethyl)-

Product 1

HCID 66746794HCID 66746794, compound

Procedure

Prepared as in Example 24a from 4-(hydroxymethyl)cyclohexanecarboxylic acid and propan-2-amine as a colorless oil (57%). 1H NMR (400 MHz, DMSO-d6) δ 1.00 (d, J=7.6 Hz, 6H), 1.22-2.08 (m, 9H), 2.12 (m, 1H), 3.28 (t, J=7.6 Hz, 2H), 3.79 (m, 1H), 4.34 (s, 1H), 7.43 (s, 1H). MS 200 (MH+).

Sources & evidence

ORD record
ord-d97f85586db94442a411440bbf149c65
Source dataset
uspto-grants-2015_04
Patent number
US09000054B2

Reaction notes

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