Methylamine hydrochloride → HCID 66747062, compound

HRID 1467180Notes

Reaction equation

HRID 1467180 reaction equation
[C:1]([C:3]1[C:18]([N+:19]([O-:21])=[O:20])=[CH:17][CH:16]=[CH:15][C:4]=1[O:5][CH:6]1[CH2:11][CH2:10][CH:9]([C:12]([OH:14])=O)[CH2:8][CH2:7]1)#[N:2].Cl.[CH3:23][NH2:24]>>[C:1]([C:3]1[C:18]([N+:19]([O-:21])=[O:20])=[CH:17][CH:16]=[CH:15][C:4]=1[O:5][CH:6]1[CH2:7][CH2:8][CH:9]([C:12]([NH:24][CH3:23])=[O:14])[CH2:10][CH2:11]1)#[N:2]

Participants

3

Reactant 2

HCID 6364545Methylamine hydrochlorideHCID 66746578HCID 66746578, compound

Product 1

HCID 66747062HCID 66747062, compound

Procedure

Prepared as in Example 24a from 4-(2-cyano-3-nitrophenoxy)cyclohexanecarboxylic acid (Example 154d) and methylamine hydrochloride as an orange solid (80%). MS 304 (MH+).

Sources & evidence

ORD record
ord-53d77995cdd446c6a3cdb319e1c6e56e
Source dataset
uspto-grants-2015_04
Patent number
US09000054B2

Reaction notes

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