Acetyl chloride → HCID 66745984, compound

HRID 1467211Notes

Reaction equation

HRID 1467211 reaction equation
[Cl-].[C:2]([C:4]1[C:16]([N+:17]([O-:19])=[O:18])=[CH:15][CH:14]=[CH:13][C:5]=1[O:6][CH2:7][C@H:8]1[CH2:12][CH2:11][CH2:10][NH2+:9]1)#[N:3].[C:20](Cl)(=[O:22])[CH3:21]>>[C:20]([N:9]1[CH2:10][CH2:11][CH2:12][C@@H:8]1[CH2:7][O:6][C:5]1[CH:13]=[CH:14][CH:15]=[C:16]([N+:17]([O-:19])=[O:18])[C:4]=1[C:2]#[N:3])(=[O:22])[CH3:21]

Participants

3

Reactant 2

HCID 6367Acetyl chlorideHCID 66746622HCID 66746622, compound

Product 1

HCID 66745984HCID 66745984, compoundYield 100%

Procedure

Prepared as in Example 165b from (R)-2-((2-cyano-3-nitrophenoxy)methyl)pyrrolidinium chloride and acetyl chloride in 100% yield as a yellow syrup. MS 290 (MH+).

Sources & evidence

ORD record
ord-30b7a6a81b474f80a09c369158ca0573
Source dataset
uspto-grants-2015_04
Patent number
US09000054B2

Reaction notes

Loading…