Butyryl chloride → HCID 66745740, compound

HRID 1467213Notes

Reaction equation

HRID 1467213 reaction equation
Cl.[N+:2]([C:5]1[CH:12]=[CH:11][CH:10]=[C:9]([O:13][CH2:14][CH:15]2[CH2:19][CH2:18][NH:17][CH2:16]2)[C:6]=1[C:7]#[N:8])([O-:4])=[O:3].[C:20](Cl)(=[O:24])[CH2:21][CH2:22][CH3:23]>>[N+:2]([C:5]1[CH:12]=[CH:11][CH:10]=[C:9]([O:13][CH2:14][CH:15]2[CH2:19][CH2:18][N:17]([C:20](=[O:24])[CH2:21][CH2:22][CH3:23])[CH2:16]2)[C:6]=1[C:7]#[N:8])([O-:4])=[O:3]

Participants

3

Reactant 2

HCID 8855Butyryl chlorideHCID 66745747HCID 66745747, compound

Product 1

HCID 66745740HCID 66745740, compoundYield 100%

Procedure

Prepared as in Example 165b from 2-nitro-6-(pyrrolidin-3-ylmethoxy)benzonitrile hydrochloride (Example 181d) and butyryl chloride in 100% yield as an orange solid. MS 318 (MH+).

Sources & evidence

ORD record
ord-450092ad19d848cab5ae07c3d18c4cf0
Source dataset
uspto-grants-2015_04
Patent number
US09000054B2

Reaction notes

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