Butyryl chloride → HCID 66746002, compound

HRID 1467229Notes

Reaction equation

HRID 1467229 reaction equation
[Cl-].[C:2]([C:4]1[C:16]([N+:17]([O-])=O)=[CH:15][CH:14]=[CH:13][C:5]=1[O:6][CH2:7][C@@H:8]1[CH2:12][CH2:11][CH2:10][NH2+:9]1)#[N:3].[C:20](Cl)(=[O:24])[CH2:21][CH2:22][CH3:23]>>[NH2:17][C:16]1[CH:15]=[CH:14][CH:13]=[C:5]([O:6][CH2:7][C@@H:8]2[CH2:12][CH2:11][CH2:10][N:9]2[C:20](=[O:24])[CH2:21][CH2:22][CH3:23])[C:4]=1[C:2]#[N:3]

Participants

3

Reactant 2

HCID 8855Butyryl chlorideHCID 66747036HCID 66747036, compound

Product 1

HCID 66746002HCID 66746002, compoundYield 90%

Procedure

Prepared as in Example 191a from (S)-2-((2-cyano-3-nitrophenoxy)methyl)pyrrolidinium chloride (Example 191b) and butyryl chloride to in 90% yield as a white solid. MS 288 (MH+).

Sources & evidence

ORD record
ord-f6bc4ae4a5684c429693133668c8fe47
Source dataset
uspto-grants-2015_04
Patent number
US09000054B2

Reaction notes

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