Methyl Isocyanate → HCID 66746319, compound

HRID 1467230Notes

Reaction equation

HRID 1467230 reaction equation
[Cl-].[C:2]([C:4]1[C:16]([N+:17]([O-])=O)=[CH:15][CH:14]=[CH:13][C:5]=1[O:6][CH2:7][C@@H:8]1[CH2:12][CH2:11][CH2:10][NH2+:9]1)#[N:3].[CH3:20][N:21]=[C:22]=[O:23]>>[NH2:17][C:16]1[C:4]([C:2]#[N:3])=[C:5]([CH:13]=[CH:14][CH:15]=1)[O:6][CH2:7][C@@H:8]1[CH2:12][CH2:11][CH2:10][N:9]1[C:22]([NH:21][CH3:20])=[O:23]

Participants

3

Reactant 2

HCID 12228Methyl IsocyanateHCID 66747036HCID 66747036, compound

Product 1

HCID 66746319HCID 66746319, compoundYield 53%

Procedure

Prepared as in Example 191a from (S)-2-((2-cyano-3-nitrophenoxy)methyl)pyrrolidinium chloride (Example 191b) and methyl isocyanate in 53% yield as a white solid. MS 275 (MH+).

Sources & evidence

ORD record
ord-f5199d8e8a63483e955fce749a3672e3
Source dataset
uspto-grants-2015_04
Patent number
US09000054B2

Reaction notes

Loading…