Dinitrobenzonitrile → HCID 66746948, compound

HRID 1467239Notes

Reaction equation

[OH:1][CH2:2][C:3]([CH3:17])([CH3:16])[C:4]([NH:6][CH2:7][C:8]1[CH:13]=[CH:12][C:11]([O:14][CH3:15])=[CH:10][CH:9]=1)=[O:5].[N+:18]([C:21]1[CH:28]=[CH:27][CH:26]=[C:25]([N+]([O-])=O)[C:22]=1[C:23]#[N:24])([O-:20])=[O:19]>>[C:23]([C:22]1[C:21]([N+:18]([O-:20])=[O:19])=[CH:28][CH:27]=[CH:26][C:25]=1[O:1][CH2:2][C:3]([CH3:17])([CH3:16])[C:4]([NH:6][CH2:7][C:8]1[CH:9]=[CH:10][C:11]([O:14][CH3:15])=[CH:12][CH:13]=1)=[O:5])#[N:24]

Participants

Reactant 2

HCID 520718Dinitrobenzonitrile

HCID 66747275HCID 66747275, compound

Product 1

HCID 66746948HCID 66746948, compoundYield 95%

Procedure

Prepared as in Example 197c from 3-hydroxy-N-(4-methoxybenzyl)-2,2-dimethylpropanamide (Example 201d) and 2,6-dinitrobenzonitrile in 95% yield as a pale yellow solid. MS 384 (MH+).

Sources & evidence

ORD record: ord-3c0dea7ccb774385bc55be92456ba4e1
Source dataset: uspto-grants-2015_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09000054B2

Reaction notes

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