Chlorosulfamic acid → HCID 86657477, compound

HRID 1467262Notes

Reaction equation

HRID 1467262 reaction equation
[NH2:1][C:2]1[CH:9]=[CH:8][CH:7]=[C:6]([O:10][CH2:11][CH2:12][CH2:13][CH2:14][O:15][Si](C(C)(C)C)(C)C)[C:3]=1[C:4]#[N:5].[S:23](Cl)(=[O:26])(=[O:25])[NH2:24]>O>[S:23](=[O:26])(=[O:25])([O:15][CH2:14][CH2:13][CH2:12][CH2:11][O:10][C:6]1[CH:7]=[CH:8][CH:9]=[C:2]([NH:1][S:23](=[O:26])(=[O:25])[NH2:24])[C:3]=1[C:4]#[N:5])[NH2:24]

Participants

4

Reactant 2

HCID 24499Chlorosulfamic acidHCID 66747022HCID 66747022, compound

Product 1

HCID 86657477HCID 86657477, compoundYield 63%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Prepared as in Example 197a from 2-amino-6-(4-(tert-butyldimethylsilyloxy)butoxy)benzonitrile (Example 211b) and sulfamoyl chloride in 63% yield. MS 382 (M++H2O).

Sources & evidence

ORD record
ord-8ee41ea13fc14fa3b2dda112a12c8dc5
Source dataset
uspto-grants-2015_04
Patent number
US09000054B2

Reaction notes

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