Chlorosulfamic acid → HCID 86657480, compound

HRID 1467266Notes

Reaction equation

HRID 1467266 reaction equation
[NH2:1][C:2]1[CH:9]=[CH:8][CH:7]=[C:6]([O:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][O:16][Si](C(C)(C)C)(C)C)[C:3]=1[C:4]#[N:5].[S:24](Cl)(=[O:27])(=[O:26])[NH2:25]>>[S:24](=[O:27])(=[O:26])([O:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][O:10][C:6]1[CH:7]=[CH:8][CH:9]=[C:2]([NH:1][S:24](=[O:27])(=[O:26])[NH2:25])[C:3]=1[C:4]#[N:5])[NH2:25]

Participants

3

Reactant 2

HCID 24499Chlorosulfamic acidHCID 66746845HCID 66746845, compound

Product 1

HCID 86657480HCID 86657480, compoundYield 26%

Procedure

Prepared as in Example 197a from 2-amino-6-(5-(tert-butyldimethylsilyloxy)pentyloxy)benzonitrile (Example 213b) and sulfamoyl chloride in 26% yield. MS 379 (MH+).

Sources & evidence

ORD record
ord-11162339dbc44984a76296a21207313c
Source dataset
uspto-grants-2015_04
Patent number
US09000054B2

Reaction notes

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