HCID 86681279, compound → HCID 178490581, compound

Participants

Reaction Steps

A vial containing 3-(1,1-dioxido-3,6-dihydro-2H-thiopyran-4-yl)-N-[(3R)-1-(2-fluoro-6-methoxybenzyl)piperidin-3-yl]-1-trityl-1H-indazole-5-carboxamide (100 mg, 0.132 mmol) was charged with ethyl acetate (20 mL) to yield a homogenous solution. The resulting volume was continuously recycled through a 30 mm 10% Pd/C cartridge on a CatCart Thalesnano instrument (flow rate: 1 mL/min; temperature: 60° C.; pressure: 60 bar).

Provenance & Evidence