HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Pyridinecarboxaldehyde → HCID 70652323, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Pyridinecarboxaldehyde | HCID 14273 | — |
| Reactant | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Reactant | HCID 70652246 | HCID 70652246 | — |
| Catalyst | Acetic Acid | HCID 176 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 70652323 | HCID 70652323 | — |
Reaction Steps
In a flask, dichloromethane (1 mL) and acetic acid (2 drops) was added to (R)-3-(2,3-dihydrobenzofuran-5-yl)-N-(piperidin-3-yl)-1H-indazole-5-carboxamide (12 mg) and picolinaldehyde (7 mg). The reaction was stirred for 15 minutes. Sodium triacetoxyborohydride (28 mg) was added in one portion. The reaction was stirred overnight. The reaction was concentrated in vacuo and purified using prep LC/MS.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08999957B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-51c0c1fd7d5242308e553c7b2439c043 |
| Source note | uspto-grants-2015_04 |