HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzaldehyde → HCID 178519069, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzaldehyde | HCID 240 | — |
| Reactant | 4-Amino-1,3-dihydro-2-benzofuran-1-one | HCID 12284649 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178519069 | HCID 178519069 | 63.2% |
Reaction Steps
4-aminoisobenzofuran-1(3H)-one (600 mg, 4 mmol), benzaldehyde (427 mg, 4 mmol) were added to methanol (20 mL) and stirred under reflux overnight, then the mixture was evaporated under reduced pressure and the residue was dried in vacuum. 600 mg of crude product (E)-4-(benzylideneamino)isobenzofuran-1(3H)-one was obtained which was used for the next synthetic step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08999987B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-a8f62db85ca7486486f91d901fb6d1a7 |
| Source note | uspto-grants-2015_04 |