tert-Butyl Formate → HCID 101043260, compound

HRID 1467795Notes

Reaction equation

HRID 1467795 reaction equation
[NH2:1][C:2]1[CH:10]=[C:9]2[C:5]([CH:6]=[N:7][N:8]2[C:11]([O:13][C:14]([CH3:17])([CH3:16])[CH3:15])=[O:12])=[CH:4][CH:3]=1.[CH:18](OC(C)(C)C)=O>>[N+:1]([C:2]1[CH:10]=[C:9]2[C:5]([CH:6]=[N:7][N:8]2[C:11]([O:13][C:14]([CH3:17])([CH3:16])[CH3:15])=[O:12])=[CH:4][CH:3]=1)#[C-:18]

Participants

3

Reactant 2

HCID 61207tert-Butyl FormateHCID 120186071-BOC-6-AMINO-INDAZOLE

Product 1

HCID 101043260HCID 101043260, compound

Procedure

Intermediate 8 was prepared in a similar manner as Intermediate 6 from tert-butyl 6-amino-1H-indazole-1-carboxylate. 1H NMR (400 MHz, CDCl3) δ 8.28 (1H, s), 8.20 (1H, s), 7.76 (1H, d, J=8.34 Hz), 7.28-7.40 (1H, m), 1.74 (9H, s) ppm. MS (ESI) m/z: 144 (M+H-Boc)+.

Sources & evidence

ORD record
ord-afcc909725794f34817f2609d1736c93
Source dataset
uspto-grants-2015_04
Patent number
US09000172B2

Reaction notes

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