2-Hydrazinopyridine → HCID 178515580, compound

HRID 1467929Notes

Reaction equation

HRID 1467929 reaction equation
[F:1][C:2]([F:18])([F:17])[C:3]1[CH:4]=[C:5]([CH:14]=[CH:15][CH:16]=1)[C:6]([CH2:8][C:9]([O:11]CC)=O)=O.[NH:19]([C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][N:22]=1)[NH2:20]>C(O)C>[N:22]1[CH:23]=[CH:24][CH:25]=[CH:26][C:21]=1[N:19]1[C:9]([OH:11])=[CH:8][C:6]([C:5]2[CH:14]=[CH:15][CH:16]=[C:3]([C:2]([F:1])([F:17])[F:18])[CH:4]=2)=[N:20]1

Participants

4

Reactant 2

HCID 786452-HydrazinopyridineHCID 2063905Ethyl 3-oxo-3-[3-(trifluoromethyl)phenyl]propanoate

Product 1

HCID 178515580HCID 178515580, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

Ethyl 3-trifluoromethylbenzoylacetate (10 mmol, manufactured by Aldrich) and ethanol (10 mL) were charged in a 100 mL round-bottom flask to which a solution of 2-hydrazinopyridine (10 mmol, manufactured by Aldrich) in ethanol (10 mL) was then added.

Workup

  1. additionwas then added

Sources & evidence

ORD record
ord-dbc0e58068584fd6b218c396b71d217d
Source dataset
uspto-grants-2015_04
Patent number
US09000176B2

Reaction notes

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