HCID 51038404, compound → HCID 51038833, compound

HRID 1467933Notes

Reaction equation

HRID 1467933 reaction equation
[C:1](=[O:26])([O:7][C:8]1[N:12]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=2)[N:11]=[C:10]([C:19]2[CH:24]=[CH:23][CH:22]=[C:21](I)[CH:20]=2)[CH:9]=1)[O:2][C:3]([CH3:6])([CH3:5])[CH3:4].C(=O)(OC(C)(C)C)OC1N(C2C=CC=CN=2)N=C([C:40]2[CH:45]=[CH:44][C:43](Br)=[CH:42][CH:41]=2)C=1>>[C:1](=[O:26])([O:2][C:3]([CH3:6])([CH3:5])[CH3:4])[O:7][C:8]1[N:12]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=2)[N:11]=[C:10]([C:19]2[CH:20]=[C:21]([C:40]3[CH:45]=[CH:44][CH:43]=[CH:42][CH:41]=3)[CH:22]=[CH:23][CH:24]=2)[CH:9]=1

Participants

3

Reactant 2

HCID 51038404HCID 51038404, compoundHCID 51038614HCID 51038614, compound

Product 1

HCID 51038833HCID 51038833, compoundYield 89%

Procedure

The title compound was prepared in the same manner as in Example C-1, except that an equimolar amount of 3-(3-iodophenyl)-1-(pyridin-2-yl)-1H-pyrazol-5-yl tert-butyl carbonate (23) prepared in Example B-4 was used in place of Compound 21 prepared in Example B-2.

Sources & evidence

ORD record
ord-76f17c8a2e7647e58e656cde12f9675b
Source dataset
uspto-grants-2015_04
Patent number
US09000176B2

Reaction notes

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