2-Chloro-5-hydroxypyridine → HCID 86696181, compound

HRID 1467966Notes

Reaction equation

HRID 1467966 reaction equation
[Cl:1][C:2]1[N:7]=[CH:6][C:5]([OH:8])=[CH:4][CH:3]=1.O[CH:10]1[CH2:14][CH2:13][N:12]([C:15]([O:17][C:18]([CH3:21])([CH3:20])[CH3:19])=[O:16])[CH2:11]1>>[C:18]([O:17][C:15]([N:12]1[CH2:13][CH2:14][CH:10]([O:8][C:5]2[CH:6]=[N:7][C:2]([Cl:1])=[CH:3][CH:4]=2)[CH2:11]1)=[O:16])([CH3:21])([CH3:19])[CH3:20]

Participants

3

Reactant 2

HCID 8198212-Chloro-5-hydroxypyridineHCID 44169391-Boc-3-pyrrolidinol

Product 1

HCID 86696181HCID 86696181, compound

Procedure

The title compound was prepared by following the similar procedure as described in intermediate-6, using 6-chloropyridin-3-ol and tert-butyl 3-hydroxypyrrolidine-1-carboxylate; MS: 299.0 (M+1)

Sources & evidence

ORD record
ord-3b6e4f5a8f854693a05695d3915dfcaa
Source dataset
uspto-grants-2015_04
Patent number
US09000175B2

Reaction notes

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