Dimethylamine → N,N-dimethyl-1H-indole-5-carboxamide

HRID 1467969Notes

Reaction equation

[NH:1]1[C:9]2[C:4](=[CH:5][C:6]([C:10]([OH:12])=O)=[CH:7][CH:8]=2)[CH:3]=[CH:2]1.[CH3:13][NH:14][CH3:15]>>[CH3:13][N:14]([CH3:15])[C:10]([C:6]1[CH:5]=[C:4]2[C:9](=[CH:8][CH:7]=1)[NH:1][CH:2]=[CH:3]2)=[O:12]

Participants

Reactant 2

HCID 674Dimethylamine

HCID 742801H-Indole-5-Carboxylic Acid

Product 1

HCID 19803690N,N-dimethyl-1H-indole-5-carboxamide

Procedure

The title compound was prepared by following the similar procedure as described in Intermediate-10, using 1H-indole-5-carboxylic acid and dimethylamine (0.330 g, 56.6%); MS: 189.1 (M+1).

Sources & evidence

ORD record: ord-e5f1eac9361e480b8fb4b006d74b4ff6
Source dataset: uspto-grants-2015_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09000175B2

Reaction notes

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