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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1467981Generated: October 25, 2026

5-(Methylsulfonyl)-1H-indole → tert-Butyl 4-((6-(5-(methylsulfonyl)-1H-indol-1-yl)pyridin-3-yl)amino)-piperidine-1-carboxylate

https://huagongshe.com/reaction/1467981

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(Methylsulfonyl)-1H-indoleHCID 14973230—
ReactantTert-butyl 4-((6-bromopyridin-3-yl)amino)piperidine-1-carboxylateHCID 86602140—
Producttert-Butyl 4-((6-(5-(methylsulfonyl)-1H-indol-1-yl)pyridin-3-yl)amino)-piperidine-1-carboxylateHCID 86696183—

Reaction Steps

The title compound was prepared by following the similar procedure as described in Intermediate-27 using tert-butyl 4-((6-bromopyridin-3-yl)amino)piperidine-1-carboxylate and 5-(methylsulfonyl)-1H-indole; MS: 415.2 (M−56).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09000175B2
Source datasetuspto-grants-2015_04
ORD IDord-b8a86f90f42c496eb92448d37fa76720
Source noteuspto-grants-2015_04