HCID 63749495, compound → HCID 67615560, compound
Reaction equation
Cl[C:2]1[N:7]=[CH:6][C:5]([O:8][CH:9]2[CH2:13][CH2:12][N:11]([C:14]([O:16][C:17]([CH3:20])([CH3:19])[CH3:18])=[O:15])[CH2:10]2)=[CH:4][CH:3]=1.[OH:21][CH2:22][CH2:23][NH:24][C:25]([C:27]1[CH:28]=[C:29]2[C:33](=[CH:34][CH:35]=1)[NH:32][CH:31]=[CH:30]2)=[O:26]>>[OH:21][CH2:22][CH2:23][NH:24][C:25]([C:27]1[CH:28]=[C:29]2[C:33](=[CH:34][CH:35]=1)[N:32]([C:2]1[N:7]=[CH:6][C:5]([O:8][CH:9]3[CH2:13][CH2:12][N:11]([C:14]([O:16][C:17]([CH3:20])([CH3:19])[CH3:18])=[O:15])[CH2:10]3)=[CH:4][CH:3]=1)[CH:31]=[CH:30]2)=[O:26]Participants
3
Procedure
The title compound was prepared by following the similar procedure as described in Intermediate-27 using tert-butyl 3-((6-chloropyridin-3-yl)oxy)pyrrolidine-1-carboxylate and N-(2-hydroxyethyl)-1H-indole-5-carboxamide; MS: 466.5 (M+)
Sources & evidence
- ORD record
- ord-558ce038b96e4653aabd2e7bdc6b6721
- Source dataset
- uspto-grants-2015_04
- Patent number
- US09000175B2
Reaction notes
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