2,4-Dibromo-1,3-thiazole → HCID 86696190, compound

HRID 1467992Notes

Reaction equation

HRID 1467992 reaction equation
[OH:1][CH2:2][CH:3]1[CH2:8][CH2:7][N:6]([C:9]([O:11][C:12]([CH3:15])([CH3:14])[CH3:13])=[O:10])[CH2:5][CH2:4]1.Br[C:17]1[S:18][CH:19]=[C:20]([Br:22])[N:21]=1>>[Br:22][C:20]1[N:21]=[C:17]([O:1][CH2:2][CH:3]2[CH2:8][CH2:7][N:6]([C:9]([O:11][C:12]([CH3:15])([CH3:14])[CH3:13])=[O:10])[CH2:5][CH2:4]2)[S:18][CH:19]=1

Participants

3

Reactant 2

HCID 27632972,4-Dibromo-1,3-thiazoleHCID 2764081Tert-butyl 4-(hydroxymethyl)piperidine-1-carboxylate

Product 1

HCID 86696190HCID 86696190, compound

Procedure

The title compound was prepared by following the similar procedure as described in Intermediate-42, using tert-butyl 4-(hydroxymethyl)piperidine-1-carboxylate and 2,4-dibromothiazole (0.124 g, 39%); MS: 377.3 (M+1).

Sources & evidence

ORD record
ord-2a4828e2da1a422d8759c1255fe0fcc0
Source dataset
uspto-grants-2015_04
Patent number
US09000175B2

Reaction notes

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