HCID 64088099, compound → HCID 63253034, compound

Participants

Reaction Steps

To a stirred solution of N-(1H-indol-5-yl)isobutyramide (0.42 g, 2.9 mmol) in acetic acid (10 mL), sodium cynoborohydride (0.29 g, 4.6 mmol) was added at 0° C., and the reaction mixture was stirred at room temperature for 2-3 h. The reaction was quenched with water and neutralized by 50% NaOH solution, extracted with diethyl ether. The organic layer was separated and concentrated in vacuo to give N-(indolin-5-yl)isobutyramide (0.122 g, 28.5%); MS: 205.1 (M+1).

Provenance & Evidence