Ethanamine, 2,2,2-trifluoro- → HCID 55228844, compound

HRID 1468006Notes

Reaction equation

HRID 1468006 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][C:6]([C:10]([OH:12])=O)=[CH:7][CH:8]=2)[CH:3]=[CH:2]1.[F:13][C:14]([F:18])([F:17])[CH2:15][NH2:16]>>[F:13][C:14]([F:18])([F:17])[CH2:15][NH:16][C:10]([C:6]1[CH:5]=[C:4]2[C:9](=[CH:8][CH:7]=1)[NH:1][CH:2]=[CH:3]2)=[O:12]

Participants

3

Reactant 2

HCID 9773Ethanamine, 2,2,2-trifluoro-HCID 742801H-Indole-5-Carboxylic Acid

Product 1

HCID 55228844HCID 55228844, compound

Procedure

The title compound was prepared by following the similar procedure as described in Intermediate-10 using 1H-indole-5-carboxylic acid and 2,2,2-trifluoroethanamine (0.93 g, 62%); MS: 243 (M+).

Sources & evidence

ORD record
ord-aa21f3086556423ba41ee760ee5a4623
Source dataset
uspto-grants-2015_04
Patent number
US09000175B2

Reaction notes

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