Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1468009Generated: October 25, 2026

5-(Methylsulfonyl)-1H-indole → tert-Butyl-4-((6-(5-(methylsulfonyl)-1H-indol-1-yl)pyridin-3-yl) methoxy)piperidine-1-carboxylate

https://huagongshe.com/reaction/1468009

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(Methylsulfonyl)-1H-indoleHCID 14973230—
Reactanttert-Butyl 4-((6-chloropyridin-3-yl)methoxy)piperidine-1-carboxylateHCID 45786862—
Producttert-Butyl-4-((6-(5-(methylsulfonyl)-1H-indol-1-yl)pyridin-3-yl) methoxy)piperidine-1-carboxylateHCID 67615679—

Reaction Steps

The title compound was prepared by following a procedure described in Intermediate-27 by using tert-butyl 4-((6-chloropyridin-3-yl)methoxy)piperidine-1-carboxylate and 5-(methylsulfonyl)-1H-indole (0.410 g, 27.70%); MS: 386.32 (M−100).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09000175B2
Source datasetuspto-grants-2015_04
ORD IDord-38c463916d614b81a2ef8995c6eb05bd
Source noteuspto-grants-2015_04