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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1468013Generated: October 25, 2026

5-(Methanesulfonyl)-2,3-dihydro-1H-indole → tert-Butyl-4-(4-(5-(methylsulfonyl)indolin-1-yl)phenoxy)piperidine-1-carboxylate

https://huagongshe.com/reaction/1468013

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(Methanesulfonyl)-2,3-dihydro-1H-indoleHCID 2736136—
Reactant1-BOC-4-(4-bromophenoxy)piperidineHCID 46739006—
Producttert-Butyl-4-(4-(5-(methylsulfonyl)indolin-1-yl)phenoxy)piperidine-1-carboxylateHCID 67608798—

Reaction Steps

The title compound was prepared by following the similar procedure as described in Intermediate-27 using tert-butyl-4-(4-bromophenoxy)piperidine-1-carboxylate and 5-(methylsulfonyl)indoline (0.11 g, 35%); MS: 373 (M−100).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09000175B2
Source datasetuspto-grants-2015_04
ORD IDord-4d6807a380ac49bb82f1befc55ad4d2a
Source noteuspto-grants-2015_04