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HRID 1468020作成日：2026年10月25日

N,N-dimethyl-1H-indole-5-carboxamide → tert-Butyl 4-((6-(5-(dimethylcarbamoyl)-1H-indol-1-yl)pyridin-3-yl) amino)piperidine-1-carboxylate

https://huagongshe.com/reaction/1468020

反応式

関与物質

役割名称HCID仕込み量
反応物N,N-dimethyl-1H-indole-5-carboxamideHCID 19803690—
反応物Tert-butyl 4-((6-bromopyridin-3-yl)amino)piperidine-1-carboxylateHCID 86602140—
生成物tert-Butyl 4-((6-(5-(dimethylcarbamoyl)-1H-indol-1-yl)pyridin-3-yl) amino)piperidine-1-carboxylateHCID 86696195—

反応手順

The title compound was prepared by following the similar procedure as described in Example-1 by using tert-butyl 4-((6-bromopyridin-3-yl)amino)piperidine-1-carboxylate (intermediate-5) and N,N-dimethyl-1H-indole-5-carboxamide (intermediate-12).

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US09000175B2
出典データセットuspto-grants-2015_04
ORD IDord-ae15553ca3cf465ea39edb82a17e34ac
出典メモuspto-grants-2015_04