N,N-dimethyl-2,3-dihydro-1H-indole-5-carboxamide → HCID 67616421, compound

HRID 1468024Notes

Reaction equation

HRID 1468024 reaction equation
Cl[C:2]1[N:7]=[CH:6][C:5]([O:8][CH:9]2[CH2:14][CH2:13][N:12]([C:15]([O:17][C:18]([CH3:21])([CH3:20])[CH3:19])=[O:16])[CH2:11][CH2:10]2)=[CH:4][CH:3]=1.[CH3:22][N:23]([CH3:35])[C:24]([C:26]1[CH:27]=[C:28]2[C:32](=[CH:33][CH:34]=1)[NH:31][CH2:30][CH2:29]2)=[O:25]>>[C:18]([O:17][C:15]([N:12]1[CH2:13][CH2:14][CH:9]([O:8][C:5]2[CH:6]=[N:7][C:2]([N:31]3[C:32]4[C:28](=[CH:27][C:26]([C:24](=[O:25])[N:23]([CH3:22])[CH3:35])=[CH:34][CH:33]=4)[CH2:29][CH2:30]3)=[CH:3][CH:4]=2)[CH2:10][CH2:11]1)=[O:16])([CH3:21])([CH3:20])[CH3:19]

Participants

3

Reactant 2

HCID 43142510N,N-dimethyl-2,3-dihydro-1H-indole-5-carboxamideHCID 86696180Tert-butyl 4-((6-chloropyridin-3-yl)oxy)piperidine-1-carboxylate

Product 1

HCID 67616421HCID 67616421, compound

Procedure

The title compound was prepared by following the similar procedure as described in Example-1 by using tert-butyl 4-((6-chloropyridin-3-yl)oxy)piperidine-1-carboxylate (intermediate-6) and N,N-dimethylindoline-5-carboxamide (intermediate-13).

Sources & evidence

ORD record
ord-ef8772c4668348c3b3efcaa979b9e04d
Source dataset
uspto-grants-2015_04
Patent number
US09000175B2

Reaction notes

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