Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1468025Generated: October 26, 2026

5-(Methanesulfonyl)-2,3-dihydro-1H-indole → tert-Butyl-4-(((6-(5-(methylsulfonyl)indolin-1-yl)pyridin-3-yl)oxy)-methyl)piperidine-1-carboxylate

https://huagongshe.com/reaction/1468025

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(Methanesulfonyl)-2,3-dihydro-1H-indoleHCID 2736136—
Reactanttert-Butyl 4-{[(6-chloropyridin-3-yl)oxy]methyl}piperidine-1-carboxylateHCID 59718534—
Producttert-Butyl-4-(((6-(5-(methylsulfonyl)indolin-1-yl)pyridin-3-yl)oxy)-methyl)piperidine-1-carboxylateHCID 67609048—

Reaction Steps

The title compound was prepared by following the similar procedure as described in Example-1 by using 5-(methylsulfonyl)indoline (intermediate-26) and tert-butyl 4-(((6-chloropyridin-3-yl)oxy)methyl)piperidine-1-carboxylate (intermediate-29).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09000175B2
Source datasetuspto-grants-2015_04
ORD IDord-befd76fcebdd46928bd36fa3068c13df
Source noteuspto-grants-2015_04