Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1468026Generated: October 26, 2026

N,N-dimethyl-1H-indole-5-carboxamide → tert-butyl 4-(((6-(5-(dimethylcarbamoyl)-1H-indol-1-yl)pyridin-3-yl)oxy) methyl)piperidine-1-carboxylate

https://huagongshe.com/reaction/1468026

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,N-dimethyl-1H-indole-5-carboxamideHCID 19803690—
Reactanttert-Butyl 4-{[(6-chloropyridin-3-yl)oxy]methyl}piperidine-1-carboxylateHCID 59718534—
Producttert-butyl 4-(((6-(5-(dimethylcarbamoyl)-1H-indol-1-yl)pyridin-3-yl)oxy) methyl)piperidine-1-carboxylateHCID 67807780—

Reaction Steps

The title compound was prepared by following the similar procedure as described in Example-1 by using N,N-dimethyl-1H-indole-5-carboxamide (intermediate-12) and tert-butyl-4-(((6-chloropyridin-3-yl)oxy)methyl)piperidine-1-carboxylate (Intermediate 29).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09000175B2
Source datasetuspto-grants-2015_04
ORD IDord-10756cd892af4d799ca37ef89e6b5ff5
Source noteuspto-grants-2015_04