methyl 1H-indole-5-carboxylate → HCID 67616028, compound

HRID 1468037Notes

Reaction equation

HRID 1468037 reaction equation
Cl[C:2]1[N:7]=[CH:6][C:5]([O:8][CH:9]2[CH2:14][CH2:13][N:12]([C:15]([O:17][C:18]([CH3:21])([CH3:20])[CH3:19])=[O:16])[CH2:11][CH2:10]2)=[CH:4][CH:3]=1.[NH:22]1[C:30]2[C:25](=[CH:26][C:27]([C:31]([O:33][CH3:34])=[O:32])=[CH:28][CH:29]=2)[CH:24]=[CH:23]1>>[CH3:34][O:33][C:31]([C:27]1[CH:26]=[C:25]2[C:30](=[CH:29][CH:28]=1)[N:22]([C:2]1[CH:3]=[CH:4][C:5]([O:8][CH:9]3[CH2:14][CH2:13][N:12]([C:15]([O:17][C:18]([CH3:21])([CH3:20])[CH3:19])=[O:16])[CH2:11][CH2:10]3)=[CH:6][N:7]=1)[CH:23]=[CH:24]2)=[O:32]

Participants

3

Reactant 2

HCID 2737635methyl 1H-indole-5-carboxylateHCID 86696180Tert-butyl 4-((6-chloropyridin-3-yl)oxy)piperidine-1-carboxylate

Product 1

HCID 67616028HCID 67616028, compound

Procedure

The title compound was prepared by following the similar procedure as described in Example-1 using tert-butyl 4-((6-chloropyridin-3-yl)oxy)piperidine-1-carboxylate (intermediate-6) and methyl 1H-indole-5-carboxylate (0.615 g, 21%).

Sources & evidence

ORD record
ord-e134f25395714b00bc1960828b296c8b
Source dataset
uspto-grants-2015_04
Patent number
US09000175B2

Reaction notes

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