HCID 67615677, compound → HCID 86696202, compound

HRID 1468038Notes

Reaction equation

HRID 1468038 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][C:6]([CH2:10][NH:11][C:12](=[O:16])[CH:13]([CH3:15])[CH3:14])=[CH:7][CH:8]=2)[CH:3]=[CH:2]1.Cl[C:18]1[N:23]=[CH:22][C:21]([O:24][CH:25]2[CH2:30][CH2:29][N:28]([C:31]([O:33][C:34]([CH3:37])([CH3:36])[CH3:35])=[O:32])[CH2:27][CH2:26]2)=[CH:20][CH:19]=1>>[C:34]([O:33][C:31]([N:28]1[CH2:27][CH2:26][CH:25]([O:24][C:21]2[CH:22]=[N:23][C:18]([N:1]3[C:9]4[C:4](=[CH:5][C:6]([CH2:10][NH:11][C:12](=[O:16])[CH:13]([CH3:14])[CH3:15])=[CH:7][CH:8]=4)[CH:3]=[CH:2]3)=[CH:19][CH:20]=2)[CH2:30][CH2:29]1)=[O:32])([CH3:37])([CH3:35])[CH3:36]

Participants

3

Reactant 2

HCID 67615677HCID 67615677, compound2×HCID 86696180Tert-butyl 4-((6-chloropyridin-3-yl)oxy)piperidine-1-carboxylate2×

Product 1

HCID 86696202HCID 86696202, compound

Procedure

The title compound was prepared by following the similar procedure as described in Example-1 using N-((1H-indol-5-yl)methyl) isobutyramide (intermediate 3) and tert-butyl 4-((6-chloropyridin-3-yl)oxy)piperidine-1-carboxylate (intermediate 6) (0.103 g, 21.77%).

Sources & evidence

ORD record
ord-db0a673a22634b94afc90d39e9d1115e
Source dataset
uspto-grants-2015_04
Patent number
US09000175B2

Reaction notes

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