HCID 86696204, compound → HCID 67807393, compound

HRID 1468041Notes

Reaction equation

HRID 1468041 reaction equation
[CH3:1][S:2]([C:5]1[CH:6]=[C:7]2[C:11](=[CH:12][CH:13]=1)[N:10]([C:14]1[N:19]=[CH:18][C:17]([CH2:20][O:21][CH:22]3[CH2:27][CH2:26][N:25]([C:28]#[N:29])[CH2:24][CH2:23]3)=[CH:16][CH:15]=1)[CH:9]=[CH:8]2)(=[O:4])=[O:3].[OH:30][NH:31][C:32](=N)[CH3:33]>>[CH3:33][C:32]1[N:29]=[C:28]([N:25]2[CH2:24][CH2:23][CH:22]([O:21][CH2:20][C:17]3[CH:18]=[N:19][C:14]([N:10]4[C:11]5[C:7](=[CH:6][C:5]([S:2]([CH3:1])(=[O:3])=[O:4])=[CH:13][CH:12]=5)[CH:8]=[CH:9]4)=[CH:15][CH:16]=3)[CH2:27][CH2:26]2)[O:30][N:31]=1

Participants

3

Reactant 2

HCID 86696204HCID 86696204, compound2×HCID 178465666HCID 178465666, compound

Product 1

HCID 67807393HCID 67807393, compound

Procedure

The title compound was prepared by following the similar procedure as described in Example-4 using 4-((6-(5-(methylsulfonyl)-1H-indol-1-yl)pyridin-3-yl)methoxy)piperidine-1-carbonitrile (intermediate 38) and N-hydroxyacetimidamide (0.014 g, 8%).

Sources & evidence

ORD record
ord-fdc08bb348b747c3841da3db94155e85
Source dataset
uspto-grants-2015_04
Patent number
US09000175B2

Reaction notes

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