tert-Butyl 4-{[(6-chloropyridin-3-yl)oxy]methyl}piperidine-1-carboxylate → HCID 67805344, compound

HRID 1468044Notes

Reaction equation

HRID 1468044 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][C:6]([NH:10][C:11](=[O:15])[CH:12]([CH3:14])[CH3:13])=[CH:7][CH:8]=2)[CH:3]=[CH:2]1.[C:16]([O:20][C:21]([N:23]1[CH2:28][CH2:27][CH:26]([CH2:29][O:30][C:31]2[CH:32]=[N:33][C:34](Cl)=[CH:35][CH:36]=2)[CH2:25][CH2:24]1)=[O:22])([CH3:19])([CH3:18])[CH3:17]>>[C:16]([O:20][C:21]([N:23]1[CH2:28][CH2:27][CH:26]([CH2:29][O:30][C:31]2[CH:32]=[N:33][C:34]([N:1]3[C:9]4[C:4](=[CH:5][C:6]([NH:10][C:11](=[O:15])[CH:12]([CH3:13])[CH3:14])=[CH:7][CH:8]=4)[CH:3]=[CH:2]3)=[CH:35][CH:36]=2)[CH2:25][CH2:24]1)=[O:22])([CH3:19])([CH3:17])[CH3:18]

Participants

3

Reactant 2

HCID 59718534tert-Butyl 4-{[(6-chloropyridin-3-yl)oxy]methyl}piperidine-1-carboxylate2×HCID 64088099HCID 64088099, compound2×

Product 1

HCID 67805344HCID 67805344, compound

Procedure

The title compound was prepared by following the similar procedure as described in Example-1 using N-(1H-indol-5-yl)isobutyramide (intermediate 10) and tert-butyl 4-(((6-chloropyridin-3-yl)oxy)methyl)piperidine-1-carboxylate (intermediate 29).

Sources & evidence

ORD record
ord-729ee0a070834bec95dd6efe413e300c
Source dataset
uspto-grants-2015_04
Patent number
US09000175B2

Reaction notes

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