HCID 60304372, compound → HCID 67809371, compound

HRID 1468046Notes

Reaction equation

HRID 1468046 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][C:6]([NH:10][C:11]([CH:13]3[CH2:15][CH2:14]3)=[O:12])=[CH:7][CH:8]=2)[CH:3]=[CH:2]1.Cl[C:17]1[N:22]=[CH:21][C:20]([O:23][CH:24]2[CH2:29][CH2:28][N:27]([C:30]([O:32][C:33]([CH3:36])([CH3:35])[CH3:34])=[O:31])[CH2:26][CH2:25]2)=[CH:19][CH:18]=1>>[C:33]([O:32][C:30]([N:27]1[CH2:26][CH2:25][CH:24]([O:23][C:20]2[CH:21]=[N:22][C:17]([N:1]3[C:9]4[C:4](=[CH:5][C:6]([NH:10][C:11]([CH:13]5[CH2:14][CH2:15]5)=[O:12])=[CH:7][CH:8]=4)[CH:3]=[CH:2]3)=[CH:18][CH:19]=2)[CH2:29][CH2:28]1)=[O:31])([CH3:36])([CH3:34])[CH3:35]

Participants

3

Procedure

The title compound was prepared by following the similar procedure as described in Example-1 using N-(1H-indol-5-yl)cyclopropanecarboxamide (intermediate-02) and tert-butyl 4-((6-chloropyridin-3-yl)oxy)piperidine-1-carboxylate (intermediate-06).

Sources & evidence

ORD record
ord-67fe1cdf930f443fb4ede527196beb59
Source dataset
uspto-grants-2015_04
Patent number
US09000175B2

Reaction notes

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