HCID 63749495, compound → HCID 67616138, compound

HRID 1468050Notes

Reaction equation

HRID 1468050 reaction equation
[OH:1][CH2:2][CH2:3][NH:4][C:5]([C:7]1[CH:8]=[C:9]2[C:13](=[CH:14][CH:15]=1)[NH:12][CH:11]=[CH:10]2)=[O:6].Cl[C:17]1[CH:22]=[CH:21][C:20]([O:23][CH:24]2[CH2:29][CH2:28][N:27]([CH2:30][C:31]([F:34])([CH3:33])[CH3:32])[CH2:26][CH2:25]2)=[CH:19][N:18]=1>>[F:34][C:31]([CH3:33])([CH3:32])[CH2:30][N:27]1[CH2:26][CH2:25][CH:24]([O:23][C:20]2[CH:21]=[CH:22][C:17]([N:12]3[C:13]4[C:9](=[CH:8][C:7]([C:5]([NH:4][CH2:3][CH2:2][OH:1])=[O:6])=[CH:15][CH:14]=4)[CH:10]=[CH:11]3)=[N:18][CH:19]=2)[CH2:29][CH2:28]1

Participants

3

Reactant 2

HCID 63749495HCID 63749495, compoundHCID 86696205HCID 86696205, compound

Product 1

HCID 67616138HCID 67616138, compound

Procedure

The title compound was prepared by following the similar procedure as described in Example-1 using N-(2-hydroxyethyl)-1H-indole-5-carboxamide (intermediate-19) and 2-Chloro-5-((1-(2-fluoro-2-methylpropyl)piperidin-4-yl)oxy)pyridine (intermediate-54).

Sources & evidence

ORD record
ord-e9e2db8c4e9a4c17a547c764047fc718
Source dataset
uspto-grants-2015_04
Patent number
US09000175B2

Reaction notes

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