HCID 67609316, compound → HCID 67639864, compound

HRID 1468052Notes

Reaction equation

HRID 1468052 reaction equation
Cl[C:2]1[N:7]=[CH:6][C:5]([O:8][CH:9]2[CH2:14][CH2:13][N:12]([C:15]([O:17][C:18]([CH3:21])([CH3:20])[CH3:19])=[O:16])[CH2:11][CH2:10]2)=[CH:4][CH:3]=1.[NH:22]1[C:30]2[C:25](=[CH:26][C:27]([N:31]3[CH2:35][CH2:34][O:33][C:32]3=[O:36])=[CH:28][CH:29]=2)[CH:24]=[CH:23]1>>[C:18]([O:17][C:15]([N:12]1[CH2:13][CH2:14][CH:9]([O:8][C:5]2[CH:6]=[N:7][C:2]([N:22]3[C:30]4[C:25](=[CH:26][C:27]([N:31]5[CH2:35][CH2:34][O:33][C:32]5=[O:36])=[CH:28][CH:29]=4)[CH:24]=[CH:23]3)=[CH:3][CH:4]=2)[CH2:10][CH2:11]1)=[O:16])([CH3:21])([CH3:20])[CH3:19]

Participants

3

Reactant 2

HCID 67609316HCID 67609316, compoundHCID 86696180Tert-butyl 4-((6-chloropyridin-3-yl)oxy)piperidine-1-carboxylate

Product 1

HCID 67639864HCID 67639864, compound

Procedure

The title compound was prepared by following the similar procedure as described in Example-1 using tert-butyl 4-((6-chloropyridin-3-yl)oxy)piperidine-1-carboxylate (intermediate-06) and 3-(1H-indol-5-yl)oxazolidin-2-one (intermediate-59) (0.390 g, 63%).

Sources & evidence

ORD record
ord-18de0e4967f046b086a2c88555021751
Source dataset
uspto-grants-2015_04
Patent number
US09000175B2

Reaction notes

Loading…