HCID 68555576, compound → HCID 86696206, compound

HRID 1468053Notes

Reaction equation

HRID 1468053 reaction equation
Cl[C:2]1[N:7]=[CH:6][C:5]([O:8][CH:9]2[CH2:14][CH2:13][N:12]([C:15]([O:17][C:18]([CH3:21])([CH3:20])[CH3:19])=[O:16])[CH2:11][CH2:10]2)=[CH:4][CH:3]=1.[CH3:22][C:23]1[C:31]2[C:26](=[CH:27][CH:28]=[C:29]([S:32]([CH3:35])(=[O:34])=[O:33])[CH:30]=2)[NH:25][CH:24]=1>>[C:18]([O:17][C:15]([N:12]1[CH2:13][CH2:14][CH:9]([O:8][C:5]2[CH:6]=[N:7][C:2]([N:25]3[C:26]4[C:31](=[CH:30][C:29]([S:32]([CH3:35])(=[O:34])=[O:33])=[CH:28][CH:27]=4)[C:23]([CH3:22])=[CH:24]3)=[CH:3][CH:4]=2)[CH2:10][CH2:11]1)=[O:16])([CH3:21])([CH3:20])[CH3:19]

Participants

3

Reactant 2

HCID 68555576HCID 68555576, compoundHCID 86696180Tert-butyl 4-((6-chloropyridin-3-yl)oxy)piperidine-1-carboxylate

Product 1

HCID 86696206HCID 86696206, compound

Procedure

The title compound was prepared by following the similar procedure as described in Example-1 by using tert-butyl 4-((6-chloropyridin-3-yl)oxy)piperidine-1-carboxylate (intermediate-6) and 3-methyl-5-(methylsulfonyl)-1H-indole (intermediate-23).

Sources & evidence

ORD record
ord-d352bbf7d50c488f977a16d528ffce39
Source dataset
uspto-grants-2015_04
Patent number
US09000175B2

Reaction notes

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