HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-butyl 5-(2-oxopyrrolidin-1-yl)-1H-indole-1-carboxylate → tert-Butyl-4-((6-(5-(2-oxopyrrolidin-1-yl)-1H-indol-1-yl)pyridin-3-yl) oxy)piperidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-butyl 5-(2-oxopyrrolidin-1-yl)-1H-indole-1-carboxylate | HCID 67616327 | — |
| Reactant | Tert-butyl 4-((6-chloropyridin-3-yl)oxy)piperidine-1-carboxylate | HCID 86696180 | — |
| Product | tert-Butyl-4-((6-(5-(2-oxopyrrolidin-1-yl)-1H-indol-1-yl)pyridin-3-yl) oxy)piperidine-1-carboxylate | HCID 67807051 | — |
Reaction Steps
The title compound was prepared by following the similar procedure as described in Example-1 using tert-butyl 4-((6-chloropyridin-3-yl)oxy)piperidine-1-carboxylate (intermediate-6) and tert-butyl 5-(2-oxopyrrolidin-1-yl)-1H-indole-1-carboxylate (intermediate-27) (0.011 g, 6%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09000175B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-b60a315bdd9a4f3392585efe2b42917c |
| Source note | uspto-grants-2015_04 |