Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1468067Generated: October 26, 2026

5-(Methanesulfonyl)-2,3-dihydro-1H-indole → tert-Butyl-4-((4-(5-(methylsulfonyl)indolin-1-yl)thiazol-2-yl)oxy)-piperidine-1-carboxylate

https://huagongshe.com/reaction/1468067

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(Methanesulfonyl)-2,3-dihydro-1H-indoleHCID 2736136—
Reactanttert-Butyl 4-((4-bromothiazol-2-yl)oxy)piperidine-1-carboxylateHCID 86696185—
Producttert-Butyl-4-((4-(5-(methylsulfonyl)indolin-1-yl)thiazol-2-yl)oxy)-piperidine-1-carboxylateHCID 67609089—

Reaction Steps

The title compound was prepared by following the similar procedure as described in Example-1 using 5-(methylsulfonyl)indoline (intermediate 26) and tert-Butyl 4-((4-bromothiazol-2-yl)oxy)piperidine-1-carboxylate (intermediate 46).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09000175B2
Source datasetuspto-grants-2015_04
ORD IDord-10e01075cdf94794ab8593bc2304a349
Source noteuspto-grants-2015_04