Aluminum(III) Chloride → HCID 66826441, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 5-amino-3-[(3,4-dimethoxyphenyl)methyl]-8-(2-furyl)-1-methyl-[1,2,4]triazolo[5,1-f]purin-2-one (0.1 g, 0.237 mmol), 1,2-dichlorobenzene (5 ml), and aluminium chloride (0.095 g, 0.711 mmol) were stirred at and heated at 160° C. for 45 minutes. Reaction mixture was cooled to room temperature and purified by LCMS to obtain pure 5-amino-8-(2-furyl)-1-methyl-3H-[1,2,4]triazolo[5,1-f]purin-2-one (0.025 g, 39%).

Provenance & Evidence