Boron tribromide → HCID 89157678, compound

Participants

Reaction Conditions

Reaction Steps

To a suspension of 6-methoxy-5-methylbenzo[d]thiazole (5B) (160 mg, 0.89 mmol) in dichloromethane (5 mL) was added boron tribromide (1 M in dichlormethane, 1.8 ml) at 0° C. The reaction mixture was stirred at 0° C. for 2 h. The reaction was quenched by adding a saturated NaHCO3 solution, extracted with dichlormethane and trace MeOH. The organic layer was dried over MgSO4, filtered, concentrated and purified by silica gel column (0-100% Ethyl acetate/hexanes). LCMS-ESI+: calc'd for C8H7NOS: 166.0 (M+H+). Found: 166.2 (M+H+).

Provenance & Evidence