Bromine → HCID 70981708, compound

HRID 1468676Notes

Reaction equation

HRID 1468676 reaction equation
[CH3:1][C:2]1[C:3]([OH:11])=[CH:4][C:5]2[S:9][CH:8]=[N:7][C:6]=2[CH:10]=1.[Br:12]Br>C(O)(=O)C>[Br:12][C:4]1[C:5]2[S:9][CH:8]=[N:7][C:6]=2[CH:10]=[C:2]([CH3:1])[C:3]=1[OH:11]

Participants

4

Reactant 2

HCID 24408BromineHCID 89157678HCID 89157678, compound

Product 1

HCID 70981708HCID 70981708, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

To a suspension of 5-methylbenzo[d]thiazol-6-ol (5C) (140 mg, 0.84 mmol) in acetic acid (5 ml), was added bromine (40 μL) slowly. The reaction mixture was stirred at room temperature for 1 h. The precipitate was collected, washed with acetic acid, water and dried under high vacuum. LCMS-ESI+: calc'd for C8H6BrNOS: 244.0 (M+H+). Found: 244.1 (M+H+).

Workup

  1. customThe precipitate was collected
  2. washwashed with acetic acid, water
  3. customdried under high vacuum

Sources & evidence

ORD record
ord-06c89bc849334262b125339541205942
Source dataset
uspto-grants-2015_04
Patent number
US09006229B2

Reaction notes

Loading…