(S)-2-tert-butoxy-2-(7-(4-chlorophenyl)-5-methylbenzo[d]thiazol-6-yl)ethyl pivalate → HCID 70981621, compound

HRID 1468693Notes

Reaction equation

HRID 1468693 reaction equation
[Br:1]C1C2SC(C3CC3)=NC=2C=C(C)C=1C=C.ClC1C=C[C:21]([C:24]2C3SC=NC=3C=C(C)C=2C=C)=[CH:20]C=1.[C:36]([O:42][CH2:43][C@@H:44]([O:62][C:63]([CH3:66])([CH3:65])[CH3:64])[C:45]1[C:53]([CH3:54])=[CH:52][C:48]2[N:49]=[CH:50][S:51][C:47]=2[C:46]=1C1C=CC(Cl)=CC=1)(=[O:41])[C:37]([CH3:40])([CH3:39])[CH3:38]>>[C:36]([O:42][CH2:43][C@H:44]([C:45]1[C:53]([CH3:54])=[CH:52][C:48]2[N:49]=[C:50]([CH:24]3[CH2:21][CH2:20]3)[S:51][C:47]=2[C:46]=1[Br:1])[O:62][C:63]([CH3:66])([CH3:64])[CH3:65])(=[O:41])[C:37]([CH3:38])([CH3:40])[CH3:39]

Participants

4

Reactant 3

HCID 70980986(S)-2-tert-butoxy-2-(7-(4-chlorophenyl)-5-methylbenzo[d]thiazol-6-yl)ethyl pivalateHCID 891577997-(4-Chlorophenyl)-5-methyl-6-vinylbenzo[d]thiazoleHCID 891578377-Bromo-2-cyclopropyl-5-methyl-6-vinylbenzo[d]thiazole

Product 1

HCID 70981621HCID 70981621, compound

Procedure

Compound 18 was prepared from compound 17 by the method used to convert compound 5G to compound 5J as outlined in Example 1. LCMS-ESI+: calc'd for C22H30BrN2O3S: 468.1 (M+H+). Found: 468.2 (M+H+).

Sources & evidence

ORD record
ord-cabff24b173646288c5b52c8806e7d63
Source dataset
uspto-grants-2015_04
Patent number
US09006229B2

Reaction notes

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