反应详情

The mixture of (S)-2-(2-(benzyloxy)-7-bromo-5-methylbenzo[d]thiazol-6-yl)-2-tert-butoxyethyl pivalate (67A), Pd/C (800 mg) in EtOAc/EtOH (10 ml, 1:1) was charged into a flask with H2 balloon, and stirred at rt for 1 h. The reaction mixture was filtered over celite, concentrated down, purified by silica gel column, eluting by 0-50% EtOAc in hexanes to give 67B (850 mg).

1. additionwas charged into a flask with H2 balloon
2. filtrationThe reaction mixture was filtered over celite
3. concentrationconcentrated down
4. custompurified by silica gel column
5. washeluting by 0-50% EtOAc in hexanes