HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Ethanesulfinate → 5-ethyl-2-{4-[(1R,2R)-2-({[4-(ethylsulfonyl)benzyl]oxy}methyl)cyclopropyl]piperidin-1-yl}pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Ethanesulfinate | HCID 22986214 | — |
| Reactant | 2-[4-((1R,2R)-2-{[(4-bromobenzyl)oxy]methyl}cyclopropyl)piperidin-1-yl]-5-ethyl pyrimidine | HCID 71135272 | — |
| Product | 5-ethyl-2-{4-[(1R,2R)-2-({[4-(ethylsulfonyl)benzyl]oxy}methyl)cyclopropyl]piperidin-1-yl}pyrimidine | HCID 71473917 | — |
Reaction Steps
This compound was prepared from the product of example 54 (step A), and sodium ethanesulfinate according to the procedure from example 56. MS (ESI) m/z 444 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09006228B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-85205f6f8f604d1086e0bca0672c903d |
| Source note | uspto-grants-2015_04 |