Allyl bromide → HCID 66692984, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of phenol 12 (860 mg, 3.04 mmol) in acetone (20 mL) were added allyl bromide (0.5 mL, 4.56 mmol) and Cs2CO3 (2.0 g, 6.08 mmol) at room temperature. The mixture was stirred at 60° C. for 2 hours. The reaction mixture was cooled to room temperature and filtered off through celite. The filtrate was concentrated in vacuo. The residue was purified by silica column chromatography (Biotage) to provide the title compound 13 (906 mg, 92%).

Provenance & Evidence