2,3-Dichloro-5,6-dicyano-1,4-benzoquinone → HCID 136364497, compound

Participants

Reaction Steps

2-(2-Chloro-4-methylphenyl)-8-methyl-2,3-dihydroquinazolin-4(1H)-one (159 mg, 0.6 mmol) and 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (126 mg, 0.6 mmol) were dissolved in 5 ml of ethanol and then stirred at room temperature for 2 hours. The reaction mixture was filtered and the solid was washed with a little ethanol. This gave 108 mg (65.5% of theory) of 2-(2-chloro-4-methylphenyl)-8-methylquinazolin-4(3H)-one as a colorless said of melting point 234° C. 1H NMR (400 MHz, d6-DMSO δ, ppm) 12.54 (br. S, 1H), 8.00 (d, 1H), 7.70 (d, 1H), 7.56 (d, 1H), 7.42 (m, 2H), 7.30 (d, 1H), 2.51 (s, 3H), 2.40 (s, 3H).

Provenance & Evidence