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2,5-Dimethoxyphenylboronic acid → HCID 44219055、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2,5-Dimethoxyphenylboronic acid | HCID 2734342 | — |
| 反応物 | US10918640, Example 14 | HCID 66710496 | — |
| 生成物 | HCID 44219055 | HCID 44219055 | 83% |
反応手順
This compound was prepared by the method outlined for example 5 step 6. Thus 3-(5-Iodo-pyridin-2-yloxy)-azetidine-1-carboxylic acid pyridazin-3-ylamide (100 mg, 0.25 mmol) was reacted with 2,5-Dimethoxybenzeneboronic acid (Cas. No 107099-99-0, 69 mg, 0.38 mmol) to afford title compound (84 mg, 83%) as an off-white powder. LCMS: (Method B) RT=1.19 min; m/z=408 [M+H]+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09006269B2 |
| 出典データセット | uspto-grants-2015_04 |
| ORD ID | ord-b872c864789c47d2a2b4d2e71fe78ed8 |
| 出典メモ | uspto-grants-2015_04 |