1,2-Ethanediamine, N1,N1,N2-trimethyl- → Bis-benzyloxy benzoic acid

Participants

Reaction Steps

In another embodiment the compounds can be prepared as shown in Scheme IV. A bromo-nitrobenzene (1) can be reacted with N1,N2,N2-trimethylethane-1,2-diamine to give N1-(nitrophenyl)-N1,N2,N2-trimethylethane-1,2-diamine (2). A solution of (2) in can be subjected to hydrogenation, passed through a short pad of celite, washed with MeOH and evaporated under reduced pressure. Thiocarbodiimidazole can then be added to (2) to give the N1-(isothiocyanato-phenyl)-)—N1,N2,N2-trimethylethane-1,2-diamine (3).

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