HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → Hexahydro-2,5-methano-pentalene-3a-carbonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | Hexahydro-2,5-methanopentalene-3a(1H)-carboxylic acid | HCID 2733865 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Hexahydro-2,5-methano-pentalene-3a-carbonyl chloride | HCID 13182402 | 99.3% |
Reaction Steps
To a solution of commercially available hexahydro-2,5-methano-pentalene-3a-carboxylic acid (10 g, 0.06 mol) in dichloromethane (200 mL) was added oxalyl chloride (8.7 g, 0.066 mol). The mixture was stirred overnight and then concentrated under reduced pressure to afford the title compound as a colorless oil (11 g, 99%). MS (DCI/NH3) m/z 184 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09006275B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-4f72d9e2f0384ffe856c5ab4ac0c50e1 |
| Source note | uspto-grants-2015_04 |